Search Result

Results for "

Bombesin Receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bombesin Receptor (17) Bacterial (1) Interleukin Related (1) JNK (1)
By Research Areas:	Cancer (7) Endocrinology (1) Infection (1) Inflammation/Immunology (2) Metabolic Disease (10) Neurological Disease (3)

Inhibitors & Agonists

Peptides

Natural
Products

Targets Recommended: Bombesin Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103281

Litorin	Bombesin Receptor	Metabolic Disease
Litorin, an amphibian bombesin peptide derivative, is an **bombesin receptor** agonist. Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo .

HY-P5072

GRP (14-27) (human, porcine, canine)	Bombesin Receptor	Metabolic Disease
GRP (14-27) (human, porcine, canine) is a bombesin receptor ligand. The specific binding of GRP (14-27) is inhibited by GTP and GDP, whereas GMP was without effect .

HY-W343750

[Tyr4]-Bombesin

Bombesin Receptor Metabolic Disease

[Tyr4]-Bombesin is a Bombesin analogue, is a ligand of gastrin-releasing peptide receptor (GRPR) .
HY-103287

[D-Phe12,Leu14]-Bombesin

Bombesin Receptor Cancer

[D-Phe12,Leu14]-Bombesin is an antagonist of Bombesin Receptor. [D-Phe12,Leu14]-Bombesin can be used for the research of cancer .

[Tyr4]-Bombesin	Bombesin Receptor	Metabolic Disease
[Tyr4]-Bombesin is a Bombesin analogue, is a ligand of gastrin-releasing peptide receptor (GRPR) .

[D-Phe12,Leu14]-Bombesin	Bombesin Receptor	Cancer
[D-Phe12,Leu14]-Bombesin is an antagonist of **Bombesin Receptor*. [D-Phe12,Leu14]-Bombesin* can be used for the research of cancer .

HY-P1423

BA 1	Bombesin Receptor	Metabolic Disease Cancer
BA 1 is a potent agonist for the *bombesin* (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC₅₀s of 6, 0.4, 2.5 nM .

HY-P1423A

BA 1 TFA	Bombesin Receptor	Metabolic Disease Cancer
BA 1 TFA is a potent agonist for the *bombesin* (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC₅₀s of 6, 0.4, 2.5 nM .

HY-P0195

Bombesin 1 Publications Verification	Bombesin Receptor	Neurological Disease Metabolic Disease
Bombesin, a tetradecapeptide, plays an important role in the release of gastrin and the activation of G-protein receptors .

HY-N4247

Kuwanon G

Bombesin Receptor Bacterial Infection

Kuwanon G is a flavonoid isolated from Morus alba, acts as a bombesin receptor antagonist, with potential antimicrobial activity .
HY-101844

ML-18

Bombesin Receptor Cancer

ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC₅₀ of 4.8 μM.
HY-P0107

RC-3095

RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist . RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice .

Kuwanon G	Bombesin Receptor Bacterial	Infection
Kuwanon G is a flavonoid isolated from Morus alba, acts as a **bombesin receptor** antagonist, with potential antimicrobial activity .

ML-18	Bombesin Receptor	Cancer
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC₅₀ of 4.8 μM.

RC-3095
RC-3095 is a *bombesin/gastrin* releasing peptide receptor (GRPR) antagonist . RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice .

HY-P0107A

RC-3095 TFA	Bombesin Receptor	Inflammation/Immunology
RC-3095 TFA is a selective *bombesin/gastrin* releasing peptide receptor (GRPR) antagonist . RC-3095 TFA exerts protective effects by reducing gastric oxidative injury in the arthritic mice .

HY-N2600

Kuwanon H	Bombesin Receptor	Cancer
Kuwanon H is a flavonoid isolated from Morus alba, which acts as a potent non-peptide **bombesin receptor antagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP to GRP-preferring recepotr, with a K_i** value of 290 nM in cells .

HY-P0039

BIM-26226	Bombesin Receptor	Cancer
BIM-26226, gastrin-releasing peptide, is a potent and selective antagonist of **bombesin receptor. BIM-26226 inhibits BN- or GRP-stimulated amylase release with IC₅₀**s in the nanomolar range. BIM-26226 can be used for the research of cancer .

HY-P1685

Ranatensin	Bombesin Receptor	Endocrinology
Ranatensin is a undecapeptide and a **Bombesin Receptor** angonist, can be isolated from amphibian skin, such as the frog, Rana pipiens. Ranatensin could maintain the dynamic balance of animal blood pressure, without cross-tachyphylaxis with Angiotensin amide (HY-P2212), Bradykinin (HY-P0206), or Norepinephrine (HY-13715) .

HY-103277

BIM 23042	Bombesin Receptor	Neurological Disease Metabolic Disease
BIM 23042, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin B (HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca ²⁺ release .

HY-103277A

BIM 23042 TFA	Bombesin Receptor	Neurological Disease Metabolic Disease
BIM 23042 TFA, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin B (HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca ²⁺ release .

HY-14342

MK-5046 1 Publications Verification	Bombesin Receptor	Metabolic Disease
MK-5046 is a potent, selective and orally active Bombesin receptor subtype-3 (BRS-3) allosteric agonist with an IC₅₀ and an EC₅₀ value of 27 and 25 nM for hBRS-3, respectively. MK-5046 inhibits food intake and reduces body weight of diet-induced obese (DIO) mouse models. MK-5046 can be used for the research of obesity .

HY-14342A

(R)-MK-5046	Others	Metabolic Disease
(R)-MK-5046 is the isomer of MK-5046 (HY-14342), and can be used as an experimental control. MK-5046 is a potent, selective and orally active Bombesin receptor subtype-3 (BRS-3) allosteric agonist with an IC₅₀ and an EC₅₀ value of 27 and 25 nM for hBRS-3, respectively. MK-5046 inhibits food intake and reduces body weight of diet-induced obese (DIO) mouse models. MK-5046 can be used for the research of obesity .

HY-103544

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P	JNK Interleukin Related Bombesin Receptor	Inflammation/Immunology Cancer
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, a Substance P derivative, is a biased agonist toward neuropeptide and chemokine receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P activates G12. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P binds to IL-8 and GRP receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P inhibits ERK-2 activation, activates JNK activity. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P stimulates an increase in neutrophil migration and Ca ²⁺ mobilization. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is also a *bombesin* antagonist, and inhibits the growth of small cell lung cancer

Cat. No.	Product Name	Target	Research Area

HY-103281

Litorin	Bombesin Receptor	Metabolic Disease
Litorin, an amphibian bombesin peptide derivative, is an **bombesin receptor** agonist. Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo .

HY-P5072

GRP (14-27) (human, porcine, canine)	Bombesin Receptor	Metabolic Disease
GRP (14-27) (human, porcine, canine) is a bombesin receptor ligand. The specific binding of GRP (14-27) is inhibited by GTP and GDP, whereas GMP was without effect .

HY-W343750

[Tyr4]-Bombesin

Bombesin Receptor Metabolic Disease

[Tyr4]-Bombesin is a Bombesin analogue, is a ligand of gastrin-releasing peptide receptor (GRPR) .
HY-103287

[D-Phe12,Leu14]-Bombesin

Bombesin Receptor Cancer

[D-Phe12,Leu14]-Bombesin is an antagonist of Bombesin Receptor. [D-Phe12,Leu14]-Bombesin can be used for the research of cancer .

[Tyr4]-Bombesin	Bombesin Receptor	Metabolic Disease
[Tyr4]-Bombesin is a Bombesin analogue, is a ligand of gastrin-releasing peptide receptor (GRPR) .

[D-Phe12,Leu14]-Bombesin	Bombesin Receptor	Cancer
[D-Phe12,Leu14]-Bombesin is an antagonist of **Bombesin Receptor*. [D-Phe12,Leu14]-Bombesin* can be used for the research of cancer .

HY-P5413

[Lys3]-Bombesin	Peptides	Others
[Lys3]-Bombesin is a biological active peptide. (PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.)

HY-P1423

BA 1	Bombesin Receptor	Metabolic Disease Cancer
BA 1 is a potent agonist for the *bombesin* (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC₅₀s of 6, 0.4, 2.5 nM .

HY-P1423A

BA 1 TFA	Bombesin Receptor	Metabolic Disease Cancer
BA 1 TFA is a potent agonist for the *bombesin* (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC₅₀s of 6, 0.4, 2.5 nM .

HY-P0195

Bombesin 1 Publications Verification	Bombesin Receptor	Neurological Disease Metabolic Disease
Bombesin, a tetradecapeptide, plays an important role in the release of gastrin and the activation of G-protein receptors .

HY-P0107A

RC-3095 TFA	Bombesin Receptor	Inflammation/Immunology
RC-3095 TFA is a selective *bombesin/gastrin* releasing peptide receptor (GRPR) antagonist . RC-3095 TFA exerts protective effects by reducing gastric oxidative injury in the arthritic mice .

HY-P0039

BIM-26226	Bombesin Receptor	Cancer
BIM-26226, gastrin-releasing peptide, is a potent and selective antagonist of **bombesin receptor. BIM-26226 inhibits BN- or GRP-stimulated amylase release with IC₅₀**s in the nanomolar range. BIM-26226 can be used for the research of cancer .

HY-P1685

Ranatensin	Bombesin Receptor	Endocrinology
Ranatensin is a undecapeptide and a **Bombesin Receptor** angonist, can be isolated from amphibian skin, such as the frog, Rana pipiens. Ranatensin could maintain the dynamic balance of animal blood pressure, without cross-tachyphylaxis with Angiotensin amide (HY-P2212), Bradykinin (HY-P0206), or Norepinephrine (HY-13715) .

HY-103277

BIM 23042	Bombesin Receptor	Neurological Disease Metabolic Disease
BIM 23042, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin B (HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca ²⁺ release .

HY-103277A

BIM 23042 TFA	Bombesin Receptor	Neurological Disease Metabolic Disease
BIM 23042 TFA, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin B (HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca ²⁺ release .

HY-103544

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P	JNK Interleukin Related Bombesin Receptor	Inflammation/Immunology Cancer
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, a Substance P derivative, is a biased agonist toward neuropeptide and chemokine receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P activates G12. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P binds to IL-8 and GRP receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P inhibits ERK-2 activation, activates JNK activity. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P stimulates an increase in neutrophil migration and Ca ²⁺ mobilization. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is also a *bombesin* antagonist, and inhibits the growth of small cell lung cancer

Litorin	Alkaloids Classification of Application Fields Animals Source classification Metabolic Disease Plants Solanaceae Disease Research Fields Datura metel Linn. Indole Alkaloids	Bombesin Receptor
Litorin, an amphibian bombesin peptide derivative, is an **bombesin receptor** agonist. Litorin stimulates the contraction of smooth muscle, stimulates gastrin, gastric acid, and pancreatic secretion, and suppresses the nutriment in vivo .

Bombesin 1 Publications Verification	Structural Classification Natural Products Animals Source classification	Bombesin Receptor
Bombesin, a tetradecapeptide, plays an important role in the release of gastrin and the activation of G-protein receptors .

Kuwanon G	Infection Flavonoids Classification of Application Fields Flavones Source classification Phenols Polyphenols Plants Moraceae Disease Research Fields Morus alba Linn.	Bombesin Receptor Bacterial
Kuwanon G is a flavonoid isolated from Morus alba, acts as a **bombesin receptor** antagonist, with potential antimicrobial activity .

Kuwanon H	Flavonoids Classification of Application Fields Flavones Source classification Phenols Polyphenols Plants Moraceae Disease Research Fields Cancer Morus alba Linn.	Bombesin Receptor
Kuwanon H is a flavonoid isolated from Morus alba, which acts as a potent non-peptide **bombesin receptor antagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP to GRP-preferring recepotr, with a K_i** value of 290 nM in cells .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Bombesin Receptor

Inhibitors & Agonists

Peptides

NaturalProducts

Natural
Products